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| Symbol | Value | Change | Percentage Change |
|---|---|---|---|
| DJIA | 11,288.54 | 73.03 | 0.65% |
| NASDAQ | 2,245.38 | -6.08 | -0.27% |
| S&P 500 | 1,262.90 | 1.38 | 0.11% |
| Large Block Holder Type | Number | ||
|---|---|---|---|
| Institutions | 27 |
Total Number of Shares Held
20.94 M
% of Shares Owned by all Large Block Holders
100.00%
|
|
| Mutual Fund | 23 | ||
| Other Major | 5 | ||
| Total Number of Large Block Holders | 55 | ||
| Name | Shares | Estimated Value of Shares * | Holdings | Shares Outstanding | Turnover Rating |
|---|---|---|---|---|---|
| Flagship Ventures | 3.33 M | 34.75 M | 92.27% | 15.90% | Low |
| Highland Capital Partners LLC | 2.99 M | 31.19 M | 15.05% | 14.27% | High |
| MPM Capital, L.L.C. | 2.99 M | 31.19 M | 6.61% | 14.27% | Low |
| Atlas Venture | 2.99 M | 31.19 M | 15.58% | 14.27% | Low |
| Versant Ventures | 2.15 M | 22.41 M | 12.85% | 10.25% | Low |
| Franklin Advisers, Inc. | 867,000 | 5.20 M | 0.01% | 4.14% | Low |
| Frontier Capital Management Company, LLC | 767,850 | 4.61 M | 0.09% | 3.67% | Low |
| Stephens Investment Management, L.L.C. | 708,346 | 4.25 M | 1.80% | 3.38% | Medium |
| Millennium Management, L.L.C. | 612,523 | 2.87 M | 0.02% | 2.93% | High |
| Wasatch Advisors, Inc. | 256,440 | 1.54 M | 0.03% | 1.22% | Low |
| Name | Shares | Estimated Value of Shares * | Holdings | Shares Outstanding | Turnover Rating |
|---|---|---|---|---|---|
| Franklin Biotechnology Discovery Fund | 642,400 | 3.85 M | 1.30% | 3.07% | Low |
| Franklin Templeton Invest-Biotechnology Discovery | 108,900 | 1.14 M | 1.86% | 0.52% | Low |
| Lord Abbett Securities Trust - Micro-Cap Growth | 66,100 | 826,250.00 | 1.46% | 0.32% | High |
| Wasatch Small Cap Growth Fund | 134,710 | 808,260.00 | 0.10% | 0.64% | Medium |
| Franklin Technology Fund | 59,800 | 624,312.00 | 0.35% | 0.29% | Medium |
| Transamerica Evergreen Health Care Fund | 100,500 | 603,000.00 | 0.23% | 0.48% | Medium |
| Evergreen Health Care Fund | 90,000 | 540,000.00 | 0.23% | 0.43% | Medium |
| M Fund - Frontier Capital Appreciation | 70,600 | 423,600.00 | 0.27% | 0.34% | Low |
| Hirtle Callaghan Trust Small Capitalization Equity | 68,600 | 411,600.00 | 0.07% | 0.33% | Medium |
| ING Evergreen Health Sciences Portfolio | 59,500 | 357,000.00 | 0.20% | 0.28% | Medium |
| Name | Shares | Estimated Value of Shares * | Holdings | Shares Outstanding | Turnover Rating |
|---|---|---|---|---|---|
| Lapidus (Stanley N) | 493,539 | 2.94 M | — | 2.36% | Low |
| Lombardi (Stephen J) | 179,444 | 1.07 M | — | 0.86% | Low |
| Meyers (Thomas C) | 77,777 | 462,773.00 | — | 0.37% | Low |
| Efcavitch (J William) | 98,145 | 459,319.00 | — | 0.47% | Low |
| Mawhinney (Louise A) | 68,199 | 405,784.00 | — | 0.33% | Medium |
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